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The human body is all connected. Your foot is connected to the ankle which is connected to the knee yada yada yada. Did you know each separate part of the body is designed to to something different? Regional interdependence first coined by Dr. Gray Cook and Mike Boyle is a term coined to explain how the body interacts with itself. The simplest way to explain this is: The human body is compromised of alternating stable parts and mobile parts. Starting at the foot which is a stable area, we then go to the ankle which is a mobile area, knee (stable), Hip (mobile), Pelvis + Lumbar spine (stable), Thoracic Spine (mobile), etc. This concept is why it is important to evaluate the person as a whole and not just focusing in on one body part and explains how a problem with ankle mobility can cause havoc on the lower back. Once you understand this concept you can understand how if a body part is not performing it's role it'll cause problems elsewhere in the body.